This post covers an exciting proteomics study that suggests a mechanism of glyphosate toxicity by which the metabolite glyoxylate reacts with protein thiols thereby damaging fatty acid modifying enzymes. To make matters more interesting the sulfate/osylate transporter slc26a1 also transports glyoxylate. For all of those who have noted a sulfate connection in autism and have wondered about environmental toxins like glyphosate.
Tag: autism
Na Sulfate transporter
This post explores heavy metal inhibition of the sodium sulfate cotransporter as well as genetic variants affecting activity.
Propionate and Mitochondria
propionic acid is thought to play a role in autism. This post explores a publication that suggests that maleic acid, a metabolite of propionic acid, is the real mitochondria poison.
Miralax and antifreeze
While Miralax use to treat constipation may have its issues such as changes in the microbiome, the amount of ethylene glycol in it is no where near to drinking antifreeze.