This site is about my consulting and alternative medicine markets that I'd like to enter
We really got into this one for a while. It relates to gut health and brain health.
This post sort of grew from an exploration of valerate. It is worth our while to even bother? The 1st report comparing valerate with shorter short chain fatty acids, [1] SCFA in intestinal barrier function, relevant to so much, [2] Brief look at airway epithelial function and secretion of tissue plasminogen activator. [3] The featured… Continue reading GPR41 and GPR43
his post expands on a very extensive study of broiler chickens conducted by scientists from Belgium and the Netherlands. Part of the motivation of this new supplement was the observation that valeric acid-producing Oscillibacter valericigenes is found to be more abundant in the stools of healthy people as compared to the stools of patients with Crohn's disease. [1] The authors could have done a better job of explaining the role of glucagon like peptide 2. This post is probably also not doing such a good job either. Consult reference [2] for a good review. The major take home of this post is that the L-cells that secrete GLP2 do so by means of G protein coupled receptors of short chain fatty acids. Two of these also bind propionic acid. Another might be more selective for valeric acid.
This post examines a TessMed product that might be modified for valproic acid. Chitosan and Dextrin are not clay binders but they can form bonds with therapeutic short chain fatty acids.
This investigation was conducted by the School of Veterinary Medicine at the University of Zagreb, Croatia. This study used a total of 16 high-yielding Holstein-Friesian dairy cows averaging 680 ± 30 kg of body weight, between 2–7 years of age. The cows were fed a control diet of haylage, corn silage, and a complete feed mixture with 19% of crude protein. The dietary forage-to-concentrate ratio was5:25 and 60:40
This post started out as an exploration of use of the feed supplement trivalerate as a way of mimicking the beneficial effects of a fecal microbial transplant that can shift the gut microbiome to produce more valerate. How does a medium chain triglyceride differ from a long chain triglyceride? Images of trivalerate and tripamitate from… Continue reading Trivalerate