We were interested in the difference between methylation and acetylation and how they control histone function. Then aceylation was discovered.
Category: short chain fatty acids
We really got into this one for a while. It relates to gut health and brain health.
Propionate and Mitochondria
propionic acid is thought to play a role in autism. This post explores a publication that suggests that maleic acid, a metabolite of propionic acid, is the real mitochondria poison.
Propionic Acid,Mitophagy, L-serine
It would seem that dentritic spines have their own supply of mitochondria to produce ATP for all of the work they do. [1] More stimulation of dentritic spines leads to more mitochondria. The Li publication has some excellent images that will not be reproduced in this post. The featured image is a compilation of many Internet images merged with GIMP2.
GPR109a
This post is about GPR109a and the response to LPS. It is a direct full circle to the post called Clinoptilolite that describes a decrease in the tight junction protein ZO-1 in the feces of human endurance atheletes. CLinoptilolite decreases the loss of barrier function. Clinoptilolite cont addresses a metabolomics study demonstrating changes in β-hydroxybutyrate and other metabolites that could be ligands for GPR109a in dairy cows
FFAR1 and FFAR4
This post compares and contrasts medium to long chain fatty acid receptors with the story on the short chain fatty acid receptors.