This post points to Nrf2 as the mediator of α-LA protection against As, Hg, and Cd toxicity and GSH synthesis as an important part of the protection.
This post describes the development of an alanine coated glassy carbon electrode that can detects heavy metals Cu, Zn, Hg, and Pb, Kokab et al 2019. Heavy metals in a fluid are coated on this electrode in cathode mode. Heavy metal cations in detox solutions will theoretically electroplate on the cathode. Then the cathode becomes the anode. Square waves are used to strip the anode of plated metals into their cation form.Could this technique One Day be used to detect heavy metals in body fluids after detox?
This post explores heavy metal inhibition of the sodium sulfate cotransporter as well as genetic variants affecting activity.
Do heavy metals and Candida interact? Candida species can produce sulfides from cadmium, mercury, and lead. These metal sulfides produced synthetically may enter the brain. We do not know if fungal metal sulfides enter the brain.
This post started out exploring a model of mercury (Hg) toxicity first proposed by the Bridges Laboratory. A request was made to look at some of the transport proteins, not necessarily only in the renal tubules. The conclusion is that these transporters are rather promiscuous. The Bridges model may work for transition metal complexes as… Continue reading GSH and Hg detox