This post is about GPR109a and the response to LPS. It is a direct full circle to the post called Clinoptilolite that describes a decrease in the tight junction protein ZO-1 in the feces of human endurance atheletes. CLinoptilolite decreases the loss of barrier function. Clinoptilolite cont addresses a metabolomics study demonstrating changes in β-hydroxybutyrate and other metabolites that could be ligands for GPR109a in dairy cows
his post expands on a very extensive study of broiler chickens conducted by scientists from Belgium and the Netherlands. Part of the motivation of this new supplement was the observation that valeric acid-producing Oscillibacter valericigenes is found to be more abundant in the stools of healthy people as compared to the stools of patients with Crohn's disease.  The authors could have done a better job of explaining the role of glucagon like peptide 2. This post is probably also not doing such a good job either. Consult reference  for a good review. The major take home of this post is that the L-cells that secrete GLP2 do so by means of G protein coupled receptors of short chain fatty acids. Two of these also bind propionic acid. Another might be more selective for valeric acid.
This post examines a TessMed product that might be modified for valproic acid. Chitosan and Dextrin are not clay binders but they can form bonds with therapeutic short chain fatty acids.
This post is a melding of two related papers A 1994 Japanese paper shows activation of T cells by what they call crysotile. Cystotile is the silicate we commonly call asbestos,  A 2004 Croatian paper describes a clinical trial of clinoptilolite, a mineral that contains silica and alumina, on immune cells in immunocompromised participants. 
This investigation was conducted by the School of Veterinary Medicine at the University of Zagreb, Croatia. This study used a total of 16 high-yielding Holstein-Friesian dairy cows averaging 680 ± 30 kg of body weight, between 2–7 years of age. The cows were fed a control diet of haylage, corn silage, and a complete feed mixture with 19% of crude protein. The dietary forage-to-concentrate ratio was5:25 and 60:40